API Erythromycin Bacterial Fish Disease Medication

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Erythromycin Bacterial Fish Disease Treatment by API (Mars)

  • Open Red Sores
  • Gill Disease
  • Fin and Tail Rot
  • Mouth Fungus
  • Hemorrhagic Septicemia
  • For both freshwater and saltwater


ERYTHROMYCIN by API® is a broad spectrum treatment for control of bacterial disease such as body slime and mouth fungus, Furunculosis (open lesions and swelling), bacterial gill disease and hemorrhagic septicemia (blood spots without sign of skin damage). For use in both freshwater and saltwater aquariums. Can be used with any API Ich, fungus or parasite remedy to help prevent secondary bacterial infection. This medication will not color the aquarium water.

Note: This medication will not cause discoloration of aquarium water.

Hemorrhagic Septicemia: A bacterial infection of the bloodstream. Fish may show blood streaks on the body and fins, red patches and localized swelling.

Open Red Sores: From small ulcers to deep skin lesions. Coloring of sores can be red or grey to very dark which indicates necrotic (dying) tissue.

Fin and Tail Rot: Fins appear damaged. In severe cases fins and tail are almost completely eroded. Secondary fungal infections appearing as a white “cotton” looking growth are common.

Bacterial Gill Disease: Bright red gills and heavy breathing, as well as fish sitting at the bottom or near top of aquarium water surface.

Mouth Fungus: The appearance of fungus on the mouth and other soft tissue, with red periphery. Severe erosions will develop if left untreated.


For each 10 gallons of water, empty one packet directly into aquarium. Repeat dose after 24 hours. Wait another 24 hours then change 25% of the aquarium water. Repeat this treatment for a second time, for a total of 4 doses. Then make a final 25% water change and add fresh activated carbon or replace filter cartridge.

SIZE: 10 powder packets in package. Each package treats 100 gallons. Four doses required for full course of treatment.